Enhances liver detoxification and supports the metabolism of hormones and xenobiotics*
Calcium D-Glucarate (CDG) has been shown to promote liver detoxification by enhancing the metabolism of hormones and environmental toxins.* It also helps maintain normal cholesterol levels.*
Calcium D-Glucarate (CDG) is produced naturally in small amounts by humans. CDG supplementation has been shown to prevent the recycling of hormones and undesirable environmental toxins, thereby promoting liver detoxification and the excretion of these potentially detrimental substances.*
Other applications of CDG supplementation include the maintenance of already normal cholesterol levels and facilitating healthy hormone metabolism.*
How does it work?
Glucuronidation is the liver's normal process of attaching a glucuronic acid molecule to potentially harmful substances to detoxify and eliminate them from the body.*
During phase II liver detoxification, certain hormones and various fat-soluble toxins will undergo glucuronidation and be excreted through the bile or urine. Calcium D-Glucarate helps this elimination process to occur uninterrupted.*
The more detailed version
Upon ingestion and exposure to the acidic environment of the stomach, Calcium D-Glucarate is metabolized to form D-glucaric acid.
Calcium D-Glucarate's detoxifying and chemopreventive properties are attributable to its ability to increase glucuronidation, and the accompanying excretion of harmful compounds.*
It does so by inhibiting the enzyme beta-glucuronidase.* During Phase II detoxification, hormones and various undesirable lipid-soluble toxins are bound to glucuronic acid in the liver (glucuronidation) and excreted through the biliary tract; however, beta-glucuronidase can unbind these toxins, which makes it possible for them to be reabsorbed rather than excreted.
Inhibition of beta-glucuronidase by Calcium D-Glucarate metabolites ultimately results in potentially decreasing the risk of toxicity.*
In addition, by reducing the activity of beta-glucuronidase and the viability of harmful intestinal bacteria, the salts of D-glucaric acid have been shown to enhance enterohepatic circulation and reduce cholesterol synthesis, thus resulting in maintenance of healthy cholesterol levels.*
Take 1 capsule three times daily or as recommended by your health professional.
Ingredients per 1 capsule:
|| 62 mg
|Calcium D-Glucarate||500 mg|
Hypromellose Capsule, Leucine
Store tightly sealed at room temperature, out of reach of children.
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
If pregnant, consult your health professional before using this product.
There are no known adverse interactions or contraindications at publication date.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.